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SYCP1 Antibody

  • 货号：
    CSB-PA225456
  • 规格：
    ￥1100
  • 图片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using CSB-PA225456(SYCP1 Antibody) at dilution 1/35, on the right is treated with synthetic peptide. (Original magnification: ×200)
  • 其他：

产品详情

  • Uniprot No.：
    Q15431
  • 基因名：
  • 别名：
    Cancer/testis antigen 8 antibody; CT8 antibody; HOM TES 14 antibody; MGC104417 antibody; SCP 1 antibody; SCP-1 antibody; SCP1 antibody; SYCP 1 antibody; Sycp1 antibody; SYCP1_HUMAN antibody; Synaptonemal complex protein 1 antibody; Testicular tissue protein Li 191 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Synthetic peptide of Human SYCP1
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen affinity purification
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,IHC
  • 推荐稀释比：
    Application Recommended Dilution
    ELISA 1:1000-1:2000
    IHC 1:25-1:100
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Major component of the transverse filaments of synaptonemal complexes, formed between homologous chromosomes during meiotic prophase. Required for normal assembly of the central element of the synaptonemal complexes. Required for normal centromere pairing during meiosis. Required for normal meiotic chromosome synapsis during oocyte and spermatocyte development and for normal male and female fertility.
  • 基因功能参考文献：
    1. Crystal structure of C-terminal coiled-coil domain of SYCP1 reveals non-canonical anti-parallel dimeric structure of transverse filament at the synaptonemal complex. PMID: 27548613
    2. crystal structure of the middle part of the human synaptonemal complex protein 1 coiled-coil domain PMID: 26323297
    3. SYCP1, cTAGE1, and GTSF1 are expressed in cutaneous T-cell lymphoma, but not in normal skin or benign inflammatory dermatoses. PMID: 24850846
    4. Cancer-Testis Antigen SCP-1 mRNA is expressed in some nasopharyngeal carcinoma. PMID: 17608150
    5. an epitope derived from the cancer testis antigen HOM-TES-14/SCP1 and presented by dendritic cells to circulating CD4+ T cells PMID: 16030183

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  • 亚细胞定位：
    Nucleus. Chromosome. Chromosome, centromere.
  • 组织特异性：
    Testis.
  • 数据库链接：

    HGNC: 11487

    OMIM: 602162

    KEGG: hsa:6847

    STRING: 9606.ENSP00000358531

    UniGene: Hs.112743