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PCID2 Antibody

  • 中文名称：
    PCID2兔多克隆抗体
  • 货号：
    CSB-PA705514LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunohistochemistry of paraffin-embedded human skeletal muscle tissue using CSB-PA705514LA01HU at dilution of 1:100
    • Immunofluorescent analysis of Hela cells using CSB-PA705514LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) PCID2 Polyclonal antibody
  • Uniprot No.：
    Q5JVF3
  • 基因名：
    PCID2
  • 别名：
    CSN12 like protein antibody; CSN12-like protein antibody; DKFZp686C20226 antibody; F10 antibody; FLJ11305 antibody; FLJ99362 antibody; HT004 antibody; MGC16774 antibody; PCI domain containing 2 antibody; PCI domain containing protein 2 antibody; PCI domain-containing protein 2 antibody; PCID2 antibody; PCID2_HUMAN antibody; RP11 - 98F14.6 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human PCI domain-containing protein 2 protein (2-250AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，PCID2 Antibody (CSB-PA705514LA01HU)，的标记方式是Non-conjugated。对于PCID2 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA705514LB01HU PCID2 Antibody, HRP conjugated ELISA
    FITC CSB-PA705514LC01HU PCID2 Antibody, FITC conjugated
    Biotin CSB-PA705514LD01HU PCID2 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IHC, IF
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:20-1:200
    IF 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Required for B-cell survival through the regulation of the expression of cell-cycle checkpoint MAD2L1 protein during B cell differentiation. As a component of the TREX-2 complex, involved in the export of mRNAs to the cytoplasm through the nuclear pores (Probable). Binds and stabilizes BRCA2 and is thus involved in the control of R-loop-associated DNA damage and transcription-associated genomic instability. R-loop accumulation does not increase in PCID2-depleted cells.
  • 基因功能参考文献：
    1. Data show that PCI domain-containing protein 2 (Pcid2) controls lymphoid lineage commitment through the regulation of Snf2-related CREBBP activator protein (SRCAP) remodelling activity. PMID: 29138493
    2. Pcid2 is present in the CBP/p300-EID1 complex to control the switch balance of mouse and human embryonic stem cells through modulation of EID1 degradation. PMID: 24167073
    3. First discovery of specific novel functions for PCID2 other than mRNA export and components of the TREX-2 complex serve alternative shared roles in the regulation of nuclear transport and cell cycle progression. PMID: 24291146
    4. validated occurrence of an unusual TG 3' splice site in intron 2 PMID: 17672918
  • 亚细胞定位：
    Cytoplasm. Nucleus, nuclear pore complex.
  • 蛋白家族：
    CSN12 family
  • 数据库链接：

    HGNC: 25653

    OMIM: 613713

    KEGG: hsa:55795

    STRING: 9606.ENSP00000337405

    UniGene: Hs.508769